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high sensitivity cytokine biochip array 1  (Randox)


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    Randox high sensitivity cytokine biochip array 1
    High Sensitivity Cytokine Biochip Array 1, supplied by Randox, used in various techniques. Bioz Stars score: 95/100, based on 184 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/high sensitivity cytokine biochip array 1/product/Randox
    Average 95 stars, based on 184 article reviews
    high sensitivity cytokine biochip array 1 - by Bioz Stars, 2026-04
    95/100 stars

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    Effects of metformin on cytokine expression and ERK signaling in RPMI 2650 cancer cells in the presence of leptin. (A) Comparative cytokine array analysis of RPMI 2650 cancer cells treated with 10 ng/mL leptin alone and in combination with 10 mM metformin. 1=IL-2, 2=Serpin E1/PAI-1, 3=IL-18/IL-1FA. (B) Quantification of pERK/ERK expression levels in RPMI 2650 cancer cells treated with 10 ng/mL leptin and 10 ng/mL leptin+10 mM metformin. The expression of pERK and ERK was normalized to GAPDH expression. One-way ANOVA was performed (n=3). Data are presented as the group mean±standard deviation. ** P <0.01, *** P <0.005, and **** P <0.001. ERK, extracellular signal-regulated kinase; pERK, phosphorylated ERK; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IL, interleukin; PAI-1, plasminogen activator inhibitor-1.

    Journal: Preventive Nutrition and Food Science

    Article Title: Antitumor Effects of Metformin in Squamous Cell Carcinoma under Leptin Treatment Conditions

    doi: 10.3746/pnf.2025.30.4.312

    Figure Lengend Snippet: Effects of metformin on cytokine expression and ERK signaling in RPMI 2650 cancer cells in the presence of leptin. (A) Comparative cytokine array analysis of RPMI 2650 cancer cells treated with 10 ng/mL leptin alone and in combination with 10 mM metformin. 1=IL-2, 2=Serpin E1/PAI-1, 3=IL-18/IL-1FA. (B) Quantification of pERK/ERK expression levels in RPMI 2650 cancer cells treated with 10 ng/mL leptin and 10 ng/mL leptin+10 mM metformin. The expression of pERK and ERK was normalized to GAPDH expression. One-way ANOVA was performed (n=3). Data are presented as the group mean±standard deviation. ** P <0.01, *** P <0.005, and **** P <0.001. ERK, extracellular signal-regulated kinase; pERK, phosphorylated ERK; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IL, interleukin; PAI-1, plasminogen activator inhibitor-1.

    Article Snippet: The supernatant from RPMI 2650 cancer cells was used in the human cytokine array kit (R&D Systems) following the manufacturer’s instructions.

    Techniques: Expressing, Standard Deviation